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  3. Smoking Weed and Consuming THC-Laced Edibles Linked to Early Heart Disease, Study Finds

Smoking Weed and Consuming THC-Laced Edibles Linked to Early Heart Disease, Study Finds

Last Updated: Tuesday June 3, 2025


Cannabis edibles

(CNN) Healthy people who regularly smoked marijuana or consumed THC-laced edibles showed signs of early cardiovascular disease similar to tobacco smokers, a new small study found.

“To my knowledge, it’s the first study looking at THC’s impact on vascular function in humans,” said senior study author Matthew Springer, professor of medicine at the University of California, San Francisco.

“We’re looking at a window in the future, showing the early changes that may explain why smoking marijuana has been linked to later heart disease,” Springer said. “It appears the act of smoking and the THC itself both contribute to those changes in different ways.” 

Tetrahydrocannabinol, or THC, is the component of marijuana that provides a high. Prior research on mice found damage to blood vessels that supply oxygen to vital organs after exposure to marijuana smoke, Springer said. Whether marijuana smoke would impact the human vascular system, however, was unknown. 

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